Effectiveness of Adjunctive Hyaluronic Acid Application in Surgical Treatment of Gingival Recession Sites

The aim of this systematic scoping review was to provide scientific evidence on the efficacy and methods application hyaluronic acid (HA) in coverage gingival recessions terms recession depth (RD) reduction, clinical attachment level (CAL) gain probing (PD). An electronic search literature main databases conducted. Initially, 405 articles were identified. Finally, four studies included after process. It not possible perform a meta-analysis selected because differences among surgical treatments commercial formulations compositions HA. Both randomized controlled trials research examined type 1 treated with coronally advanced flap. In case series, either modified tunnel or laterally closed combined subepithelial connective tissue graft No significant variation found PD. Modifications CAL are connected variations RD; however, RD reduction is similar control group. HA seems improve outcomes short term, but magnitude limited. Formulations, techniques heterogeneous.